Two sample MR report
PLA2G16_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.0238078 | 0.1572362 | 0.9043333 |
| Weighted median | 3 | -0.0331097 | 0.0139041 | 0.0172520 |
| Inverse variance weighted | 3 | -0.0346158 | 0.0116593 | 0.0029882 |
| Simple mode | 3 | -0.0325541 | 0.0150807 | 0.1635246 |
| Weighted mode | 3 | -0.0323501 | 0.0142676 | 0.1515136 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0740927 | 1 | 0.7854684 |
| Inverse variance weighted | 0.0788436 | 2 | 0.9613451 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0094433 | 0.1370043 | 0.9561891 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001186 | 0 | TRUE | 0.3020402 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
